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A client starting on rifampin therapy should be instructed that the medication can cause what type of adverse effect?

  1. Yellowing of the skin

  2. Body secretions turning a red-orange color

  3. Blurred vision

  4. Hair loss

The correct answer is: Body secretions turning a red-orange color

When starting on rifampin, a client should be informed that one of the known adverse effects of this medication is that it can cause body secretions, such as urine, sweat, and tears, to turn a red-orange color. This is a harmless side effect and is not a cause for concern. The other options are incorrect as rifampin does not typically cause yellowing of the skin (A), blurred vision (C), or hair loss (D). It is important for clients to be aware of potential side effects when starting a new medication, but it's also important to not worry unnecessarily about side effects that are not likely to occur.